This is the first comprehensive study for nearly 200 years of what remains of the writings of the Presocratic philosopher Philolaus of Croton. These fragments are crucial to our understanding of one of the most influential schools of ancient philosophy, the Pythagoreans; they also show close ties with the main lines of development of Presocratic thought, and represent a significant response to thinkers such as Parmenides and Anaxagoras. Professor Huffman presents the fragments and testimonia with accompanying translations and introductory (...) chapters and interpretive commentary. He not only produces further argument for the authenticity of much that used to be neglected, but also undertakes a critique of Aristotle's testimony, opening the way for a quite new reading of fifth-century Pythagoreanism in general and of Philolaus in particular. Philolaus is revealed as a serious natural philosopher. (shrink)

This is a comprehensive, authoritative and innovative account of Pythagoras and Pythagoreanism, one of the most enigmatic and influential philosophies in the West. In twenty-one chapters covering a timespan from the sixth century BC to the seventeenth century AD, leading scholars construct a number of different images of Pythagoras and his community, assessing current scholarship and offering new answers to central problems. Chapters are devoted to the early Pythagoreans, and the full breadth of Pythagorean thought is explored including politics, religion, (...) music theory, science, mathematics and magic. Separate chapters consider Pythagoreanism in Plato, Aristotle, the Peripatetics and the later Academic tradition, while others describe Pythagoreanism in the historical tradition, in Rome and in the pseudo-Pythagorean writings. The three great lives of Pythagoras by Diogenes Laertius, Porphyry and Iamblichus are also discussed in detail, as is the significance of Pythagoras for the Middle Ages and Renaissance. (shrink)

Archytas of Tarentum is one of the three most important philosophers in the Pythagorean tradition, a prominent mathematician, who gave the first solution to the famous problem of doubling the cube, an important music theorist, and the leader of a powerful Greek city-state. He is famous for sending a trireme to rescue Plato from the clutches of the tyrant of Syracuse, Dionysius II, in 361 BC. This 2005 study was the first extensive enquiry into Archytas' work in any language. It (...) contains original texts, English translations and a commentary for all the fragments of his writings and for all testimonia concerning his life and work. In addition there are introductory essays on Archytas' life and writings, his philosophy, and the question of authenticity. Carl A. Huffman presents an interpretation of Archytas' significance both for the Pythagorean tradition and also for fourth-century Greek thought, including the philosophies of Plato and Aristotle. (shrink)

Recently, the Pythagoreans have received rather more attention, both in their own right and as part of the developing picture of Presocratic thought, than they received for much of the twentieth century. Thanks to these studies, a new and more complicated picture is emerging. This article refines this picture critically examining Aristotle's claims about Pythagorean influence on Plato, along with the related question of who among early Greek thinkers actually counts as a Pythagorean. It provides a reminder that Aristotle's account (...) of the history of earlier thought is always a history of just a part of the philosophy of his predecessors, and makes clear that the eagerness with which some present-day scholars find Pythagorean influence on later thought may be misplaced. (shrink)

In this article I want to clarify the text of one of the short maxims assigned to Pythagoras in the ancient tradition, which are known as symbola or acusmata. Before I turn to the acusma in question, it is important to understand the context in which it appears. It occurs in Chapter 17 of Book 4 of Aelian's Historical Miscellany. Aelian's work was written in the early third century a.d. in Rome, and is a ‘miscellaneous collection of anecdotes and historical (...) material’. It consists of short chapters, usually a page or less long, that are for the most part independent of one another. Chapter 17 of Book 4 is about a page long and is devoted to the sayings and doings of Pythagoras. There is no particular connection between it and the surrounding chapters, and it is clearly meant to stand on its own. The preceding chapter tells us that if we went to Callias for guidance he would turn us into drinkers, … if to Alcibiades, arrogant cheats, if to Demosthenes, orators, … if to Aristides, just men, … if to Socrates, wise men. The following chapter recounts an anecdote about Plato's arrival in Sicily and his reception by the tyrant Dionysius the Younger. The chapter that I am concerned with, Chapter 17, begins by asserting that Pythagoras taught that his ‘lineage was superior to that of ordinary mortals’. This is followed by a list of superhuman acts and traits of Pythagoras, for example his ability to be in Metapontum and Croton at the same time and his golden thigh. The second two-thirds of the chapter are then devoted to the miscellaneous teachings of Pythagoras. Most of these take the form of the brief taboos and maxims known elsewhere as symbola or acusmata, among which is the text on which I want to focus here. (shrink)

The Pythagorean Precepts by Aristotle's pupil, Aristoxenus of Tarentum, present the principles of the Pythagorean way of life that Plato praised in the Republic. They are our best guide to what it meant to be a Pythagorean in the time of Plato and Aristotle. The Precepts have been neglected in modern scholarship and this is the first full edition and translation of and commentary on all the surviving fragments. The introduction provides an accessible overview of the ethical system of the (...) Precepts and their place not only in the Pythagorean tradition but also in the history of Greek ethics as a whole. The Pythagoreans thought that human beings were by nature insolent and excessive and that they could only be saved from themselves if they followed a strictly structured way of life. The Precepts govern every aspect of life: e.g. procreation, abortion, child rearing, friendship, religion, desire and even diet. (shrink)

In a long note in his epoch-making book on ancient Pythagoreanism Walter Burkert raised some grave doubts about the authenticity of Archytas Fr. 1 which have recently been challenged in an article by A. C. Bowen. In this paper I have two goals. First, I will evaluate Burkert's doubts and the success of some of Bowen's arguments against them. Second, I will present a further consideration that both clarifies the text of the fragment and also removes the most serious problem (...) raised by Burkert. The upshot of both these points is to increase the likelihood that the fragment is authentic. I reproduce the text of just the first part of the fragment as given in DK followed by the text as it appears in the two primary sources, Nicomachus and Porphyry. (shrink)

In a long note in his epoch-making book on ancient Pythagoreanism Walter Burkert raised some grave doubts about the authenticity of Archytas Fr. 1 which have recently been challenged in an article by A. C. Bowen. In this paper I have two goals. First, I will evaluate Burkert's doubts and the success of some of Bowen's arguments against them. Second, I will present a further consideration that both clarifies the text of the fragment and also removes the most serious problem (...) raised by Burkert. The upshot of both these points is to increase the likelihood that the fragment is authentic. I reproduce the text of just the first part of the fragment as given in DK followed by the text as it appears in the two primary sources, Nicomachus and Porphyry. (shrink)

Remembering seems, to philosophers and scientists, one of the most mystifying of human activities. Yet natural language users have no problem understanding what is meant by ‘memory’. Memory is simply the ability to recall personally experienced events and certain kinds of information such as facts, names, or faces; or how to perform certain actions, like riding a bike or playing chess. It is on this basis that people sometimes make claims about themselves or others having a good or bad memory, (...) especially for things like names, numbers, or faces. Why then is memory such a mystery? Because, firstly, of its diversity: memory enables us to perform a plethora of different tasks, including the continuous interpretation of every moment of consciousness. Secondly, different forms of memory have different standards of accuracy, and often dramatically different criteria for success. (shrink)

Cheaters and noncheaters were assessed on 2 types of motivation, on perceived social norms regarding cheating, on attitudes about cheating, and on knowledge of institutional policy regarding cheating behavior. All 5 factors were significant predictors of cheating rates. In addition, cheaters were found lower in mastery motivation and higher in extrinsic motivation in courses in which they cheated than in courses in which they did not cheat. Cheaters, in courses in which they cheated, were also lower in mastery motivation and (...) higher in extrinsic motivation than were noncheaters. Finally, cheaters differed from noncheaters on perceived social norms regarding cheating, on their knowledge of institutional policy regarding cheating, and on their attitudes toward cheating. Implications of these findings for institutional interventions are discussed. (shrink)

This remarkable book presents a rich and up-to-date view of evolution that explores the far-reaching implications of Darwin's theory and emphasizes the power, significance, and relevance of evolution to our lives today. After all, we ourselves are the product of evolution, and we can tackle many of our gravest challenges -- from lethal resurgence of antiobiotic-resistant diseases to the wave of extinctions that looms before us -- with a sound understanding of the science.

Topics in Cognitive Science, Volume 13, Issue 1, Page 243-247, January 2021.

COVID-19 often manifests with different outcomes in different patients, highlighting the complexity of the host-pathogen interactions involved in manifestations of the disease at the molecular and cellular levels. In this paper, we propose a set of postulates and a framework for systematically understanding complex molecular host-pathogen interaction networks. Specifically, we first propose four host-pathogen interaction (HPI) postulates as the basis for understanding molecular and cellular host-pathogen interactions and their relations to disease outcomes. These four postulates cover the evolutionary dispositions involved (...) in HPIs, the dynamic nature of HPI outcomes, roles that HPI components may occupy leading to such outcomes, and HPI checkpoints that are critical for specific disease outcomes. Based on these postulates, an HPI Postulate and Ontology (HPIPO) framework is proposed to apply interoperable ontologies to systematically model and represent various granular details and knowledge within the scope of the HPI postulates, in a way that will support AI-ready data standardization, sharing, integration, and analysis. As a demonstration, the HPI postulates and the HPIPO framework were applied to study COVID-19 with the Coronavirus Infectious Disease Ontology (CIDO), leading to a novel approach to rational design of drug/vaccine cocktails aimed at interrupting processes occurring at critical host-coronavirus interaction checkpoints. Furthermore, the host-coronavirus protein-protein interactions (PPIs) relevant to COVID-19 were predicted and evaluated based on prior knowledge of curated PPIs and domain-domain interactions, and how such studies can be further explored with the HPI postulates and the HPIPO framework is discussed. (shrink)

The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

Previous research has shown that personal contacts are powerful intermediaries in transmitting job lead information for both job seekers and employers and therefore could contribute to various forms of gender inequality by, for example, providing higher-quality job leads to men than to women. The authors use a unique data set that includes information on the quality and source of individual job leads to explore whether the overall quality of job lead information depends solely on various attributes of recipients' contacts or (...) whether job lead quality is also conditional on gender. These data are based on a diverse sample of professional, technical, and managerial workers from California. Findings indicate that the overall quality of the respondent's job leads is a product of their gender and that of the person providing the lead. In addition, net of a variety of factors, women and men with young children at home receive significantly lower-quality job leads. (shrink)